You'll always be compromising then mate.... I have had many many rifles and currently have .204 as arguably the best fox round at the moment with my 243 as my all rounder and I do not have a deer rifle at present... I have owned about 3 x 30-06 and 2 x 308's with the 30-06 being my favourite of those 2 calibers.

The 223 is probably the best bang for buck if you are buying factory ammo and my 204 is stupidly expensive and I will be reloading that myself soon.

The 22-250 was the Roo shooters rifle of choice for years after the 243 but as the 223 is so cheap to shoot they have mostly gone to that.