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The short answer is no...... however, it depends where you go and what you do, generally front lockers will reduce your turning ability in most situations (including sand), a limited improvement may be noticeable in very soft sand when travelling "straight" ahead.
The exception to this is if you fit a auto lokka, if you have this type of lokka in the front, with a small change in your driving style, ive found it can actually be a benifit in most sand driving situations ive come across.