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Not ideal at all. Different size front to rear or side to side is bad news.
Side to side will cause issues with your LSD.
Front to rear will cause transfer case wind-up. Technically you should only be in 4WD on loose surfaces but still no good.
I actually had a case in a previous Technical Assistance job where a front wheel drive car (with electronic throttle) was accelerating itself, turned out it had larger tyres on the front which made the computer think the front wheels were travelling slower so it would try to accelerate the drive wheels to even it out.
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